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Sirna Therapeutics, Inc. was a San Francisco, California based biotechnology company that explores the use of RNA interference in human disease therapy. Sirna's development pipeline includes several small interfering RNA (siRNA) drugs, thought to stably silence the expression of specific disease-related genes. Sirna's clinical trial of an siRNA-based treatment for age-related macular degeneration is the first such trial for an siRNA drug.〔Sah D (2006). "Therapeutic potential of RNA interference for neurological disorders". ''Life Sci'' 79 (19): 1773-80. PMID 16815477〕 Sirna Therapeutics was acquired by Merck & Co. in 2006 in a cash transaction deal worth $1.1 billion.〔"(Merck & Co., Inc. Announces Completion of Acquisition of Sirna Therapeutics, Inc. )" Merck & Co. Retrieved on March 3, 2012.〕 ==Headquarters and laboratory== Sirna maintained its laboratory on the northeastern edge of Boulder, Colorado.〔"(Directions )." Sirna Therapeutics. March 11, 2006. Retrieved on March 3, 2012.〕 Originally the corporate headquarters were also located in Boulder. Sirna, at one point, launched a search for a new headquarters complex. It originally considered multiple cities, including Cambridge, Massachusetts and San Diego, California. Sirna selected San Francisco due to its proximity to various scientific institutions, its workforce, and the payroll tax exemption for biotechnology companies. Sirna's move was a part of a trend of biotechnology companies moving to San Francisco, bolstered due to a campaign to attract biotechnology companies to San Francisco and tax breaks instituted by Mayor of San Francisco Gavin Newsom. Business leaders of San Francisco who hoped that the city would have a major biotechnology presence had a positive reception to the Sirna decision.〔Gordon, Rachel and Bernadette Tansey. "(Another biotech arrival Sirna Therapeutics moving to S.F.'s Mission Bay area )." ''San Francisco Chronicle''. Saturday March 5, 2005. C1. Retrieved on March 3, 2012.〕 The mayor's office, the Chamber of Commerce, and the San Francisco Center for Economic Development contributed to bringing Sirna to San Francisco. Howard Robin, the president and chief executive officer of Sirna, said that the first wave of moves would be the ten highest ranking employees; he did not say how many employees would relocate to San Francisco. The company planned to maintain a facility in Boulder.〔 Ultimately Sirna occupied Suite 6504 at China Basin Landing, while the laboratory facilities remained in Boulder, with administrative, manufacturing, and research facilities.〔"(Boulder Campus )." Sirna Therapeutics. March 11, 2006. Retrieved on March 3, 2012.〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Sirna Therapeutics」の詳細全文を読む スポンサード リンク
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